Conversely, rs2378456 polymorphism in LPP was associated with reduced susceptibility of lung cancer in females under genotype (GC vs GG, OR = 0.37, 95% CI = 0.18–0.76, p = 0.022, power = 1.000) and dominant (GC-CC vs GG, OR = 0.44, 95% CI = 0.23–0.84, p = 0.012, power = 0.998) model. The gene discussed is LPP; the disease is lung cancer.