TGM2 and celiac disease: Tesaluu et al. (2012) have shown that anti-TG2 IgAs-rich auto-antibodies isolated from coeliac disease (CD) patients’ serum were able to reduce the binding of TG2 to HS/heparin, and that the CD autoantibodies affected the adhesion of intestinal epithelial Caco-2 cells to FN-TG2 coated wells [179,180].