Pathways in cancer were identified according to Kyoto Encyclopedia of Genes and Genomes (KEGG) repository to be highly connected to pathways related to cell–cell adhesion (adherens junctions), cell–ECM adhesion (focal adhesion), ECM–receptor interaction and regulation of the actin cytoskeleton (pink cluster) while also being connected to Wnt and p53-related pathways (blue cluster) as well as the major pro-survival pathways of mitogen-activated protein kinase (MAPK), Akt and Ras (green cluster). The gene discussed is AKT1; the disease is cancer.