AKT1 and cancer: We also tested the expression of genes responsible for actin cytoskeleton stabilization as they are implicated in cancer cell migration and invasion, namely, the Rho-GTPases Rac, RhoA, Cell division control protein-42 (Cdc42), Rho-associated kinase-1 (ROCK-1), Fascin-1 and matrix metalloproteinase-2 (MMP-2).