In the Dahl/Salt-sensitive rat, a genetic model of hypertension with kidney disease, fed with a 4.0% salt diet for 21 days, significant upregulation of pS6/S6 and p-Akt/Akt, which are corresponding to mTORC1 and mTORC2 activities in the kidney, were shown [14]. The gene discussed is AKT1; the disease is hypertensive disorder.