A statistically significant positive correlation of nesfatin-1 level and the glucose levels: fasting, at the first and at the second hours of OGTT, were observed in patients with GDM (R = 0.382, 0.514, 0.463, respectively), and in the control group (R = 0.631, 0.565, 0.490, respectively). The gene discussed is NUCB2; the disease is gestational diabetes.