Other species of green algae belonging to the genus Chlorella have also demonstrated anticancer effects: C. sorokiniana has shown to induce apoptosis in non-small cell lung cancer (NSCLC) cells through the activation of the mitochondrial-mediated apoptotic pathway associated to downregulation of BCL-2 anti-apoptotic family, which resulted in a marked reduction of tumour growth in mice [130]; C. pyrenoidosa induced antineoplastic effects in experimental breast cancer model, instead [131]. This evidence concerns the gene BCL2 and breast carcinoma.