Inhibition of MALT1 protease activity or expression of a catalytically inactive form of MALT1 dramatically reduced the viability of cell lines derived from ABC-DLBCL, while cell lines derived from other B cell lymphoma types, such as GCB-DLBCL, Burkitt's lymphoma, and marginal zone lymphoma, were not affected (22). This evidence concerns the gene MALT1 and aneurysmal bone cyst.