Furthermore, we found that GCB-DLBCL cells (BJAB and SUDHL-4 cells) with activated MALT1 protease activity presented higher basal OCR and mitochondrial SRC than the control group or the z-VRPR-fmk combined with PMA/Iono group (Supplementary Figure 2A; Figures 4E,F). The gene discussed is MALT1; the disease is diffuse large B-cell lymphoma.