The frequency of UGT1A1*6 variant was significantly higher in NAFLD group [50.0%; (OR = 1.82; 95% CI, 1.09–3.01; P = 0.02)] than in the non-NAFLD (35.5%), when compare with GG genotype (wild-type). The gene discussed is UGT1A1; the disease is metabolic dysfunction-associated steatotic liver disease.