Two studies devoted attention to other neurodegenerative disorders, such as the Machado-Joseph disease (MJD)(Gonzalez et al., 2012) (which causes symptoms like spasticity, difficulty with speech and swallowing, weakness in arms and legs, frequent urination) and mutation to VCP gene (Surampalli et al., 2015) (which along with the inclusion body myopathy it causes frontotemporal dementia). The gene discussed is VCP; the disease is Machado-Joseph disease.