MYC and cancer: We used a genetic model which, through a combination of the UAS-Gal4 (Brand and Perrimon, 1993) and Flp-FRP (Xu and Rubin, 1993) binary systems, allowed us to express MYC in the P compartment and to induce second mutations of interest later in time, so reproducing the temporal sequence that is likely to occur during cancer initiation.