In unrelated donor transplantation settings, Kawase et al. (109) suggested that donor selection made in consideration of these results might allow the separation of GVL from acute GVHD in patients with AML, ALL, or those with chronic myeloid leukemia (CML), especially in HLA-DPB1 mismatch combinations. The gene discussed is HLA-DPB1; the disease is acute graft versus host disease.