ENO1 and infection: By using conventional transmission electron microscopy (TEM), which is the only technique with resolution suitable to clearly identify and distinguish between different modes of cell secretion (20) and immunogold EM for detecting MBP-1 subcellular localization, we identified, for the first time, a major vesicle-mediated secretory process for MBP-1 release underlying the responses of eosinophils to the infection.