IL27 and infection: From the cytokines and chemokines found in serum samples with high frequencies, IL-27 is considered a pro-inflammatory cytokine, which is able to regulate Th1, Th2, and Th17 responses, as shown in experimental infections (62) The chemokines CCL5, CCL11, and CCL17 were also found in high frequencies, especially in the group with the highest parasite loads (≥100 epg).