As LDLr−/−CD1d−/− mice, which lack NKT cells, have similar cholesterol levels when fed a WTD as compared to LDLr−/− mice (46) it is likely that in Lck-Cre Atg7f/f mice, the combined effect of the lower numbers of inflammatory CD4+, CD8+, and of NKT cells inhibited the development of WTD-induced hepatic steatosis. Here, LCK is linked to fatty liver disease.