Furthermore, the expression of the transcription factor peroxisome proliferator activated receptor gamma (Pparg), which is known to be associated with hepatic steatosis (24), was decreased while the expression of sterol regulatory element binding protein 2 (Srebp2) was increased in the liver of Lck-Cre Atg7f/f mice (Figure 2J). This evidence concerns the gene PPARG and fatty liver disease.