These include: (i) angiopoietin-2 (Ang-2) receptor, Tie2, expressing monocytes (TEM), (ii) myeloid-derived suppressor cells (MDSC), (iii) tumor-associated neutrophils (TAN), and (iv) tumor- associated dendritic cells (TADC) (19). The gene discussed is ANGPT2; the disease is neoplasm.