LAG-3+CD8+ T and PD-1+CD8+ T cells increased in both TG and cornea as early as 3 days of acute infection, and on day 14-post-infection (just after the acute infection has cleared), there were significantly more LAG-3+CD8+ T cells and PD-1+CD8+ T cells in both the cornea and TG. This evidence concerns the gene CD8A and infection.