Similarly, mice deficient in the autophagy protein LC3B (MAP1-LC3B) exhibit increased IL-17-induced lung pathology upon infection with respiratory syncytial virus (RSV) and Map1lc3b−/− CD11b+ DC infected with RSV induce IL-17 secretion from CD4+ T cells in an IL-1-dependent manner (72). This evidence concerns the gene IL1A and infection.