Given that MIR3142HG knockdown was shown to significantly reduce IL-8 and CCL2 release, and to partially reduce IL-6 release in control fibroblasts, this indicates that the drop in MIR3142HG expression may be responsible for the reduced inflammatory response in IL-1β-stimulated IPF fibroblasts. Here, IL1B is linked to idiopathic pulmonary fibrosis.