TLR4 and infection: The let-7 family of miRNAs has been associated with regulation of toll-like receptor 4 (Chen et al., 2007), control of cytokine levels (Hu et al., 2009; Schulte et al., 2011; Swaminathan et al., 2012), and regulation of the NFκB pathway (Kumar et al., 2015) in response to infection.