Future studies in larger MS populations and on serum samples are however needed to explain (i) the detailed function and interrelationship of MMP-1, MMP-7, MMP-10, and MMP-12 in MS and (ii) the potential use of these molecules as biological markers during neuroinflammation -degeneration and in tissue repairing (35). This evidence concerns the gene MMP10 and myeloid sarcoma.