GPT and Hepatic steatosis: One of the first evidence of probiotics efficacy in the treatment of fatty liver was shown in a study conducted by Li et al. (2003) in which the administration of VSL#3 (a mixture of 8 lactic acid producer strains) to genetically obese mice improved liver histology, counteracted inflammation and showed a reduction of alanine aminotransferase (ALT) plasma levels.