Sepsis is characterized by the overactivation of the immune system, which involves the secretion of pro-inflammatory cytokines, such as tumor necrosis factor-α (TNF-α), interleukin 1β (IL-1β), IL-6, and the generation of oxidative stress (Riedemann et al., 2003; Pinsky, 2004; Simon and Fernández, 2009; Becerra et al., 2011). Here, TNF is linked to Sepsis.