HSPA8 and viral infectious disease: In L. vannamei, HSP10, HSP27, HSP30, HSP60, HSP70 and HSP90 mRNA were consistently or specifically expressed in response to thermal or pH stress, heavy metal exposure (Qian et al., 2012), and bacterial or viral infection (Junprung et al., 2017; Yuan et al., 2017); HSP70 promoted post-larval tolerance to heat, ammonia and metals (Sung et al., 2018), and HSC70 reduced protein aggregation and mortality after viral infection (Yuan et al., 2017).