Then, target and C-T network analysis together display that some vital compounds of SBD such as wogonin, baicalein, and scutellarin may play an important role in the treatment of NSCLC, and SBD positively aiming for some targets like Bax, iNOS, and P38 exhibits the therapeutic effects against NSCLC by anti-inflammatory, promote apoptosis and anti-angiogenesis. This evidence concerns the gene BAX and non-small cell lung carcinoma.