In addition, The T-P network and the integrated NSCLC-relates pathway indicate that the major compounds of SBD might exert anti-NSCLC effect by modulating plenty different pathways including hsa04370:VEGF signaling pathway, hsa04151:PI3K-Akt signaling pathway, hsa04115:p53 signaling pathway and hsa04064:NF-kappa B signaling pathway. Here, AKT1 is linked to non-small cell lung carcinoma.