TRIB3 and type 2 diabetes mellitus: Hence, we use the published bioinformatics tool (e.g., ENCODE) and database (e.g., STRING) to conduct this pharmacogenomic study in 1989 Chinese patients with T2DM who received blood pressure-lowering and glucose control treatments to determine whether any variants of candidate genes in the TRIB3 regulation pathway could provide a basis for an optimal treatment regimen to reduce cardiovascular complications in patients with T2DM.