A trend was also observed for increased FCN2 with high CSF Aβ42 in the MCI group, by both logistic and linear regression (β = 0.315, P = 0.058 and β = -42.573, P = 0.051, respectively, Supplementary Table 11), replicating the association of FCN2 with CSF Tau/Aβ42 in the Amsterdam Dementia Cohort and with PET amyloid in MCI in the GE067005 study. Here, FCN2 is linked to dementia.