FBXO7 and dementia: In addition, pathogenic mutations in the genes ATPase 13A2 (ATP13A2) (Bras et al., 2012), phospholipase A2 (PLA2G6) (Gregory et al., 2008) F-Box protein 7 (FBXO7) (Shojaee et al., 2008), DNA J Heat Shock Protein Family (Hsp40) Member C6 (DNAJC6) (Edvardson et al., 2012) and Vacuolar Protein Sorting 13 Homolog C (VPS13C) (Lesage et al., 2016) are linked to autosomal recessive, early-onset atypical parkinsonism that often comprises additional clinical features such as pyramidal degeneration, ataxia or dementia, with or without LBs.