SYN1 and Alzheimer disease: As shown in Figures 8C,D, the steady-state levels of synapsin I was significantly reduced in aging AD animals from both experimental groups (0.1662 ± 0.032 A.U. from 1-month-old Tg2576 mice; 0.1017 ± 0.027 A.U. from 9-months-old Tg2576 mice) in comparison with their age-matched non-transgenic littermates (0.5136 ± 0.096 A.U. from 1-month-old WT mice; 0.2952 ± 0.076 A.U. from 9-months-old WT mice, ∗p < 0.05, t-Student’s test).