GRIA2 and Seizure: The latter work by Rajasekaran et al. (2012) focuses special attention on AMPAR plasticity in a pilocarpine model of SE and confirms the expression of GluA2-lacking AMPARs both by electrophysiological and biochemical methods; however, the precise role of CP-AMPARs in sustaining epileptic seizures or epileptogenesis is still poorly understood.