Serum insulin levels were also significantly elevated in these 7 hyperglycemic mice (F = 5.614, P < 0.01, and post hoc analysis showed that both the CRS-hyperglycemia and the CRS-normoglycemia group were significantly different from the control, P < 0.01; Figure 2D), suggesting insulin resistance. The gene discussed is INS; the disease is congenital rubella syndrome.