For instance, in node-positive, poor prognosis cervical cancers, Teneurin-2 levels were increased together with CTNND1 (Noordhuis et al., 2011), a member of the catenin gene family that stabilizes E-Cadherin at epithelial adherens junctions and mediates non-canonical WNT signaling (Schackmann et al., 2013). The gene discussed is TENM2; the disease is cervical cancer.