EA with 5–20 Hz for 30 min once daily at Baihui (DU20) and Shenting (DU24) may enhance Bcl-2 at both protein and mRNA level, phosphorylated-CREB at the protein level, and the activity of glutathione peroxidase and superoxide dismutase in the hippocampus of rats after ischemic stroke (Lin et al., 2015a). This evidence concerns the gene BCL2 and ischemic stroke.