SMAD9 and hypertensive disorder: The multivariate logistic regression model showed that after adjusting for confounding factors (such as age, gender, BMI, family history of hypertension, smoking status, and drinking status), the rs6435156 and rs1048829 loci of the BMPR2 gene, the ACVRL1 gene rs121909287 locus, and the SMAD9 gene rs397514716 locus were associated with EH risk.