Senescence biomarkers accumulate in the lungs of IPF patients, and higher expression of key senescence biomarkers, such as p16INK4A (CDKN2A), DNA damage foci (γH2A.X), telomere dysfunction, and SASP factors are associated with increased disease severity [5,10]. The gene discussed is CDKN2A; the disease is idiopathic pulmonary fibrosis.