Together with the atrophic changes taking place in the visual cortex, our findings that the retina and the optic nerve are directly affected by tau pathology may explain the wealth of data linking cognitive visual changes to tauopathies [9, 10, 15, 21, 28] and may suggest that more attention should be paid towards retinal and optic nerve changes in FTD in the clinic. The gene discussed is MAPT; the disease is frontotemporal dementia.