For adenocarcinoma patients in cohort 2, however, a higher infiltration of CD3+ TILs tended was associated with a worse prognosis (HR 2.47, 95% CI 0.77–7.96; P = 0.130, log-rank P = 0.119; Fig. 4a) Interestingly, patients showing a higher infiltration of PD1+ TILs exhibited a dismal prognosis that was statistically significant (HR, 1.20, 95% CI, 1.01–11.04; P = 0.049; log-rank P = 0.039; Fig. 4b). Here, PDCD1 is linked to adenocarcinoma.