BRAF V600E mutation and wild-type in craniopharyngiomas are discriminated with an AUC curve of 0.92 and ACC of 0.94 using two radiomics features while CTNNB1 mutation and wild-type in craniopharyngiomas are distinguished with an AUC curve of 0.95 and ACC of 0.91 based on three radiomics features. Here, BRAF is linked to craniopharyngioma.