RYR2 and catecholaminergic polymorphic ventricular tachycardia: (Leenhardt et al., 1995; Postma et al., 2005) (Miyata, Ohno, Itoh, & Horie, 2018) Several responsible genes for CPVT have been identified so far, and RYR2 which encodes the cardiac ryanodine receptor (RyR2) accounts for approximately 60% of CPVT cases.