It is able to catalyse the removal of di‐methylation marks H3K9m2 and H3K27m2 on the promoters of target genes,26 and through this, regulates fibroblast growth factor‐4 (FGF‐4) expression and neural differentiation.27 KDM7A also functions as a potential tumour suppressor through blocking tumour growth and angiogenesis.28 Up to now, it remains unknown if KDM7A regulates adipogenic and osteogenic commitment of mesenchymal stem cells. Here, FGF4 is linked to neoplasm.