HMGA1 and ovarian carcinoma: HMGA1 has high expression in malignant cancer, as determined through immunohistochemistry, when comparing normal tissue to malignant ovarian cancer.93 Liu et al indicates that using short/small hairpin RNAs of HMGA1 led to decreased growth and metastasis potential of ovarian cancer.94 In a non‐invasive urinary detection test, HMGA1 is correlated with the degree of malignancy of ovarian cancer.