Studies have shown that HMGA1 expression is sustained by HPV E6/E7 proteins, and a positive autoregulatory loop has been established between these proteins in cervical cancer.96 By generating transgenic mice with HMGA1a, the following research shows that the HMGA1a protein level is increased in high‐grade cancer but not in normal uterine tissue. Here, HMGA1 is linked to cervical carcinoma.