HMGA1 and pituitary tumor: In pituitary tumours, HMGA1 transgenic mice tend to develop growth hormone/prolactin cell pituitary adenomas by inducing the expression of IL‐2 and IL‐15 proteins.36 The HMGA1 pseudogenes HMGA1P6 and HMGA1P7 act as competitive endogenous decoys for HMGA1 and contribute to pituitary tumourigenesis by increasing the level of HMGA1.37 The expression profile of microRNA in the pituitary identified a set of miRNAs that are down‐regulated, such as miR‐34b, miR‐326, miR‐432, miR‐548c‐3p, miR‐570 and miR‐603, which target HMGA1, HMGA2 and E2F1.