Compared to healthy controls, miR‐23a, along with miR‐29b, miR‐206, and miR‐455, was up‐regulated in the skeletal muscle of ALS subjects.28 In this context, miR‐23a caused a decrease in peroxisome proliferator‐activated receptor γ coactivator‐1α (PGC‐1α) protein expression in ALS tissue. Here, PPARGC1A is linked to amyotrophic lateral sclerosis.