Hereditary PCC and PGL (HPCC/PGL) are usually associated with neoplasm syndromes including multiple endocrine neoplasia (MEN 1 and MEN 2), von Hippel–Lindau (VHL), neurofibromatosis-1 (NF-1), and familial paraganglioma (FPGL). This evidence concerns the gene NF1 and multiple endocrine neoplasia type 1.