Furthermore, we examined ZNF350 expression in cDNAs prepared from paired normal and tumor tissues of 22 patients with colon adenocarcinoma (HCRT103 TissueScan qPCR Arrays; OriGene Technologies, Rockville, MD, USA), and found that colon cancer tissues have significantly reduced ZNF350 mRNA expression when compared with the surrounding normal colon tissues (Figure 6C). The gene discussed is ZNF350; the disease is colon adenocarcinoma.