NLRP3 and prion disease: The dysregulated NLRP3 inflammasome has been linked to the pathogenesis of several inflammatory diseases including gout, type 2 diabetes, cancer, cardiovascular diseases, Alzheimer’s, Parkinson’s, and prion diseases (Alcocer-Gómez and Cordero, 2017, Lee et al., 2013, Song et al., 2017).