Indeed, ShK-186 (Dalazatide; Kv1.3 Therapeutics, Inc., Seattle, WA, USA), an analog of a venom peptide from the sea anemone Stichodactyla helianthus, is a highly potent and selective Kv1.3 blocker that has shown promise in early clinical trials for the treatment of TEM cell-mediated autoimmune disease [12, 13]. Here, KCNA3 is linked to autoimmune disease.