Conversely, in NB-12, two compound heterozygous variants c.1823G > A (p.G608D, non-conservative amino acid change) and c.770A > G (p.Y257C, non-conservative amino acid change) of uncertain significance were detected in the ETFDH gene associated with glutaric aciduria type II. This evidence concerns the gene ETFDH and multiple acyl-CoA dehydrogenase deficiency.