This finding was also confirmed analyzing the p65 protein level in the FVB MMTV Neu transgenic mice, where it was strongly induced by 2.7-fold in ethanol-fed mouse tumor compared to control tumor and the p65 nuclear translocation inhibitor, IkappaB-alpha (IkBα) [27] was reduced by 80% compared to control (Fig. 3e). Here, RELA is linked to neoplasm.