CD4 and tuberculosis: Given that the combination antiretroviral therapy (cART) could reduce up to 68% TB-related deaths in TB/HIV co-infected patients [24], early initiation of cART could be considered in high-risk patients, who are also HIV positive, although cART is recommended to be started within 8 weeks of starting TB treatment if CD4+ level ≥ 50 cells/mm3 [25].