Previous studies addressing the relationship between cross-sectional [18F]FDG uptake and CSF tau levels (P-tau181p and T-tau) in patients with AD have shown mixed results: although all have shown an inverse association, some have shown no significant association [39], significant associations only for P-tau181p [40] and T-tau [41] levels, or significant associations for both [42]. The gene discussed is MAPT; the disease is Alzheimer disease.