Data from the Oncomine database (https://www.oncomine.com/) also confirmed that PLCE1 expression was increased in esophageal carcinoma, hepatocellular carcinoma, glioblastoma and renal cell carcinoma in the four published datasets, GSE92396, GSE98383, GSE90886, and GSE6357 (Fig. 1f). This evidence concerns the gene PLCE1 and carcinoma of esophagus.