PLCE1 and hereditary clear cell renal cell carcinoma: Data from the Oncomine database (https://www.oncomine.com/) also confirmed that PLCE1 expression was increased in esophageal carcinoma, hepatocellular carcinoma, glioblastoma and renal cell carcinoma in the four published datasets, GSE92396, GSE98383, GSE90886, and GSE6357 (Fig. 1f).